J. Augenstreich

da_Tracker: Automated workflow for high throughput single cell and single phagosome tracking in infected cells.

The paper introduces da_Tracker, an automated workflow for high-throughput single-cell and single-phagosome tracking in infected cells, enabling quantitative analysis of pathogen-host interactions.

Salmonella Typhimurium infection inhibits macrophage IFNbeta signaling in a TLR4-dependent manner

This study shows Salmonella Typhimurium inhibits macrophage IFNbeta signaling via TLR4, but IFNbeta does not affect host defense against STm.

BBQ methods: Streamlined workflows for Bacterial Burden Quantification in infected cells by confocal microscopy

This paper introduces two automated methods for quantifying bacterial burden in macrophages using confocal microscopy, validated with Salmonella and Mycobacterium models.

Dynamic Interplay of Autophagy and Membrane Repair During Mycobacterium tuberculosis Infection

This study investigates LC3 recruitment to Mtb-containing vacuoles in macrophages, revealing its variability and lack of correlation with autophagosome maturation or membrane repair.

Phthiocerol dimycocerosates from Mycobacterium tuberculosis increase the membrane activity of bacterial effectors and host receptors

This study shows that phthiocerol dimycocerosates (DIM) from Mycobacterium tuberculosis increase membrane activity of both bacterial effectors and host receptors, aiding immune evasion.

The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages

This study identifies the conical shape of DIM lipids as a key factor in promoting Mycobacterium tuberculosis infection of macrophages through phagocytosis.