Author

I. Secco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Schneider· 2 shared M. Giacca· 2 shared A. Cappelletto· 1 shared A. M. Shah· 1 shared A. Margariti· 1 shared A. Pooni· 1 shared A. Zampetaki· 1 shared C. M. Reumiller· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

E. Schneider

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Author profile →

2 papers

Recent·Most cited

Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

S. G. Romeo, I. Secco, E. Schneider, C. M. Reumiller, C. X. Santos, A. Pooni, X. Yin, K. Theofilatos, S. Cellone Trevelin, L. Zeng, G. E. Mann, A. Margariti, M. Mayr, A. M. Shah, M. Giacca, A. Zampetaki

This study uses human blood vessel organoids to show that CTGF is critical for maintaining microvascular integrity under metabolic stress.

bioRxiv · Sep 1, 2022Cell Biology

SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

A. Cappelletto, H. E. Allan, M. Crescente, E. Schneider, R. Bussani, H. Ali, I. Secco, S. Vodret, R. Simeone, L. Mascaretti, S. Zacchigna, T. D. Warner, M. Giacca

This paper shows that SARS-CoV-2 Spike protein activates TMEM16F in platelets, enhancing pro-coagulant activity and thrombosis, which is inhibited by Niclosamide and Clofazimine.

bioRxiv · Dec 14, 2021 · PreprintPathology