Author

S. Zacchigna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. Giacca· 2 shared A. Albini· 1 shared A. Bruno· 1 shared A. Cappelletto· 1 shared D. Baci· 1 shared D. Klatzmann· 1 shared D. M. Noonan· 1 shared D. Nehar-Belaid· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

M. Giacca

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tissue-resident uterine regulatory T cells support fetal growth

L. M. Florez, G. Fourcade, G. Darrasse-Jeze, P. Barennes, K. Gan-Fernandez, P. Regnier, D. Nehar-Belaid, T. Courau, M. G. Ruocco, S. Zacchigna, M. Giacca, J. Lion, N. Mooney, N. Tchitchek, E. Mariotti-Ferrandiz, D. Klatzmann

The paper identifies uterine tissue-resident regulatory T cells (uTregs) that support fetal growth by promoting uterine remodeling and vascular development during pregnancy.

bioRxiv · Sep 7, 2023 · PreprintImmunology

SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

A. Cappelletto, H. E. Allan, M. Crescente, E. Schneider, R. Bussani, H. Ali, I. Secco, S. Vodret, R. Simeone, L. Mascaretti, S. Zacchigna, T. D. Warner, M. Giacca

This paper shows that SARS-CoV-2 Spike protein activates TMEM16F in platelets, enhancing pro-coagulant activity and thrombosis, which is inhibited by Niclosamide and Clofazimine.

bioRxiv · Dec 14, 2021 · PreprintPathology

A polyphenol-rich extract of Olive Mill Wastewater Enhances cancer chemotherapy effects while mitigating cardiac toxicity.

A. Albini, M. M. G. Festa, N. Ring, D. Baci, M. Rehman, G. Finzi, F. Sessa, S. Zacchigna, A. Bruno, D. M. Noonan

This paper shows that a polyphenol-rich extract from olive mill wastewater enhances chemotherapy effectiveness against prostate cancer while reducing cardiac toxicity in both in vivo and in vitro models.

bioRxiv · Apr 8, 2021Cancer Biology