Author

R. Sloutsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. P. Torres-Ocampo· 1 shared B. A. Kelch· 1 shared B. Page· 1 shared C. Gaubitz· 1 shared C. Ozden· 1 shared E. A. Esposito· 1 shared E. Agnello· 1 shared E. Lapinskas· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. P. Torres-Ocampo

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2 papers

Recent·Most cited

CaMKII binds both substrates and activators at the active site

C. Ozden, R. Sloutsky, T. Mitsugi, N. Santos, E. Agnello, C. Gaubitz, J. Foster, E. Lapinskas, E. A. Esposito, T. Saneyoshi, B. A. Kelch, S. C. Garman, Y. Hayashi, M. Stratton

This study challenges a longstanding model of CaMKII activation by showing that activators and substrates bind to a single site rather than distinct S- and T-sites.

bioRxiv · Oct 25, 2020Biochemistry

Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation

R. Sloutsky, N. Dziedzic, M. J. Dunn, R. Bates, A. P. Torres-Ocampo, S. Boopathy, B. Page, J. G. Weeks, L. H. Chao, M. M. Stratton

The paper identifies 70 CaMKII transcripts in human hippocampus and shows that the hub domain regulates kinase activity through allosteric interactions.

bioRxiv · Jan 10, 2020Biochemistry