Author

S. Boopathy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

L. H. Chao· 4 shared C. M. Lugo· 2 shared Y. Ge· 2 shared A. P. Torres-Ocampo· 1 shared A. W. Smith· 1 shared B. E. Luce· 1 shared B. Page· 1 shared B. Ueberheide· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

L. H. Chao

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Opa1 and Mfn2

S. Boopathy, B. E. Luce, C. M. Lugo, P. Hakim, J. L. McDonald, H. L. Kim, J. Ponce, B. Ueberheide, L. H. Chao

This study identifies interaction interfaces between SLC25A46 and mitochondrial fusion proteins Opa1 and Mfn2 using crosslinking mass-spectrometry and AlphaFold 2 modeling.

Journal of Biological Chemistry · Oct 1, 2024Peer-reviewedBiochemistry

Absence of cardiolipin from the outer leaflet of a mitochondrial inner membrane mimic restricts Opa1-mediated fusion

Y. Ge, S. Boopathy, T. H. Nguyen, C. M. Lugo, L. H. Chao

The paper investigates how cardiolipin distribution affects mitochondrial inner membrane fusion mediated by Opa1, finding that cardiolipin in the outer leaflet is crucial for tethering and fusion.

bioRxiv · Sep 1, 2021Biophysics

Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation

R. Sloutsky, N. Dziedzic, M. J. Dunn, R. Bates, A. P. Torres-Ocampo, S. Boopathy, B. Page, J. G. Weeks, L. H. Chao, M. M. Stratton

The paper identifies 70 CaMKII transcripts in human hippocampus and shows that the hub domain regulates kinase activity through allosteric interactions.

bioRxiv · Jan 10, 2020Biochemistry

Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

Y. Ge, X. Shi, S. Boopathy, J. McDonald, A. W. Smith, L. H. Chao

The paper shows that two forms of Opa1 work together to regulate mitochondrial inner-membrane fusion, with l-Opa1 enabling docking and s-Opa1 facilitating efficient pore opening.

bioRxiv · Dec 11, 2019Biophysics