Author

R. Stripecke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kuenkele· 1 shared A. Pruss· 1 shared A. Schneider· 1 shared B. Soper· 1 shared C. E. Porter· 1 shared C. Franke· 1 shared C. Fuster-Garcia· 1 shared C. von Kaisenberg· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Kuenkele

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Author profile →

2 papers

Recent·Most cited

T-cell development and activation in humanized mice lacking mouse major histocompatibility complexes

M. Darguzyte, P. Amtczak, D. Bachurski, P. Hoelker, N. Abedpour, R. Gholaminpoorfard, H. Schlösser, K. Wennhold, M. Thelen, M. Garcia-Marquez, J. Koenig, A. Schneider, T. Braun, F. Klawonn, M. Damrat, , R. Stripecke

This study shows human T-cell development in humanized mice can occur without mouse MHCs and is enhanced by lentiviral delivery of HLA and cytokines.

bioRxiv · Mar 26, 2024 · PreprintImmunology

Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells

J. Kath, C. Franke, V. Drosdek, W. Du, V. Glaser, C. Fuster-Garcia, M. Stein, T. Zittel, S. Schulenberg, C. E. Porter, L. Andersch, A. Kuenkele, J. Alcaniz, J. Hoffmann, H. Abken, , D. L. Wagner

This paper develops a method to integrate ζ-deficient CARs into the CD3ζ gene to create functional CAR-T and CAR-NK cells with improved safety and efficacy for off-the-shelf therapies.

bioRxiv · Nov 10, 2023 · PreprintImmunology