Author

R. W. DePaolo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

D. Chac· 2 shared K. Crebs· 2 shared A. B. Rosenberg· 1 shared A. Carignano· 1 shared A. Kuchina· 1 shared A. Verma· 1 shared C. K. Yee· 1 shared C. M. Roco· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

D. Chac

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Polyunsaturated fatty acid arachidonic acid increases the virulence of gut pathogen, Yersinia enterocolitica

D. Chac, K. Crebs, C. K. Yee, R. W. DePaolo

This study shows arachidonic acid increases the virulence of Yersinia enterocolitica by enhancing its proliferation and intracellular invasion.

bioRxiv · Dec 6, 2021 · PreprintMicrobiology

Proteomic changes in bacteria caused by exposure to environmental conditions can be detected by Matrix-Assisted Laser Desorption/Ionization - Time of Flight (MALDI-ToF) Mass Spectrometry

D. Chac, M. Kordahi, L. Brettner, A. Verma, P. McCleary, K. Crebs, C. Yee, R. W. DePaolo

This study shows that MALDI-ToF MS can detect proteomic changes in bacteria exposed to different environmental conditions, revealing intra-species phenotypic differences.

bioRxiv · Jan 24, 2020 · PreprintMicrobiology

Microbial single-cell RNA sequencing by split-pool barcoding

A. Kuchina, L. M. Brettner, L. Paleologu, C. M. Roco, A. B. Rosenberg, A. Carignano, R. Kibler, M. Hirano, R. W. DePaolo, G. Seelig

The paper introduces microSPLiT, a scRNA-seq method for bacteria, and applies it to Bacillus subtilis to reveal transcriptional states and novel gene expression patterns.

bioRxiv · Dec 11, 2019Bioengineering