Author

R. W. Jain

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

E. Romanchik· 1 shared H. C. Craig· 1 shared K. A. Parham· 1 shared S. M. Kerfoot· 1 shared Y. Tesfagiorgis· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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1 shared paperImmunology

E. Romanchik

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1 paper

Recent·Most cited

Autoreactive T cells preferentially drive differentiation of non-responsive memory B cells at the expense of germinal center maintenance.

R. W. Jain, K. A. Parham, Y. Tesfagiorgis, H. C. Craig, E. Romanchik, S. M. Kerfoot

The paper compares B cell fate outcomes in responses to autoantigen MOG and foreign antigen NPOVA, showing that autoreactive T cells drive memory B cell differentiation at the expense of germinal center maintenance.

bioRxiv · Mar 23, 2018Immunology