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R. Y. Henley

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Cell Biology· 1

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Approach:experimental assay· 1 Organism:human· 1

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D. C. Wallace· 1 shared E. Seifert· 1 shared H. Gamper· 1 shared J. A. Piccirilli· 1 shared M. Wanunu· 1 shared N. Sheng· 1 shared S. Maharjan· 1 shared T. Suzuki· 1 shared

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2023-2023 · peak 1/yr

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D. C. Wallace

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1 paper

Recent·Most cited

Cell BiologybioRxivDec 9, 2023

Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology

S. Maharjan, H. Gamper, Y. Yamaki…·Y.-M. Hou

The paper shows that N1-methylation at position 9 of mt-Leu(UAA) stabilizes wild-type mt-tRNA but destabilizes pathogenic variants, suggesting methylation control could be therapeutic.

DOI 10.1038/s41467-024-53318-x

humanexperimental assay

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