T. Suzuki

Brassinosteroids function as the plant male and female reproductive hormone coordinating gene expression.

This study shows that brassinosteroids (BRs) function as reproductive hormones in Arabidopsis, regulating gene expression in both male and female reproductive tissues during fertilization.

Radicle growth regulation of root parasitic plants by auxin-related compounds

This study investigates auxin's role in radicle growth of root parasitic plants and shows that auxin manipulation can inhibit their growth.

Cold adaptation in Upper Paleolithic hunter-gatherers of eastern Eurasia

This study analyzes 42 genomes from Jomon hunter-gatherers to show they adapted to cold environments through positive selection during the Last Glacial Maximum.

Florigen-producing cells express FPF1-LIKE PROTEIN 1 that accelerates flowering and stem growth in long days with sunlight red/far-red ratio in Arabidopsis

The paper identifies FLP1 as a gene expressed in FT-producing cells in Arabidopsis that promotes flowering and stem growth under long-day conditions.

Hidden Challenges in Evaluating Spillover Risk of Zoonotic Viruses using Machine Learning Models

This study improves machine learning models for predicting zoonotic virus infectivity by expanding datasets and using large language models, showing better performance for segmented RNA viruses and post-2018 emerging viruses.

Effects of diet particle size on growth performance of the edible cricket, Teleogryllus occipitalis (Orthoptera: Gryllidae)

This study examines how diet particle size affects growth performance in edible crickets, finding that granular feed promotes better growth than powdered feed.

Alternative oxidase alleviates mitochondrial oxidative stress during limited nitrate reduction in Arabidopsis thaliana

This study shows that alternative oxidase (AOX) reduces mitochondrial oxidative stress and supports plant growth under limited nitrate reduction in Arabidopsis thaliana.

Electric-field induced sleep promotion and lifespan extension in Gaucher's disease model flies: Association with improving ER stress and autophagy

The paper exposes GD model flies to ELF-EFs, finding increased sleep and lifespan linked to improved ER stress and autophagy.

Discovering cancer stem-like cells using Spatial transcriptomic analysis: Nuclear factor I X as a novel therapeutic target for gastric cancer

This study identifies NFIX as a critical regulator of cancer stemness in gastric cancer using spatial transcriptomic analysis and shows its correlation with poor prognosis.

Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species

This study identifies deoxyphomenone biosynthesis gene clusters in Hansfordia pulvinata and related Aspergillus species, showing horizontal gene transfer and adaptive evolution in mycoparasitism.

Structural insight into bacterial co-transcriptional translation initiation

The paper reports cryo-EM structures of the translation initiation complex assembled on transcribing RNA polymerase, showing how mRNA is protected during co-transcriptional translation initiation.

Modeling platinum resistance in a stem-like patient-derived ovarian cancer sample

This study develops a patient-derived model of cisplatin resistance in ovarian cancer stem-like cells and identifies molecular and functional changes associated with resistance.

Chemical genetic interaction linking eIF5A hypusination and mitochondrial integrity

This study investigates the effects of eIF5A hypusination inhibition on mitochondrial function and identifies MPV17L2 as a key regulator involved in mitochondrial integrity.

The leucine-rich repeat receptor kinase QSK1 is a novel regulator of PRR-RBOHD complex and is employed by the bacterial effector HopF2Pto to modulate plant immunity

The paper identifies QSK1 as a novel negative regulator of PRR-RBOHD complex and shows it is targeted by the bacterial effector HopF2Pto to suppress plant immunity.

Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology

The paper shows that N1-methylation at position 9 of mt-Leu(UAA) stabilizes wild-type mt-tRNA but destabilizes pathogenic variants, suggesting methylation control could be therapeutic.

Can Colpoda travel across oceans? Salinity tolerance of resting cysts may enable global dispersal of the species.

The study investigates whether Colpoda cucullus resting cysts can tolerate saline conditions, suggesting a mechanism for oceanic dispersal of freshwater protists.

DeepLabCut-based Behavioural and Posture Analysis in a Cricket

This paper develops a system using DeepLabCut to analyze cricket behavior and posture, revealing diurnal rhythms in locomotion, feeding, and sleep-like states without human bias or physical tagging.

Transcriptomic landscape of seedstick in Arabidopsis thaliana funiculus after fertilisation

This study performs transcriptomic analysis of Arabidopsis thaliana funiculus in stk mutants to identify deregulated genes and processes involved in seed development.

Dengue virus exploits the host tRNA epitranscriptome to promote viral replication

This study shows dengue virus exploits host tRNA modifications to enhance viral replication by altering translation of pro-viral proteins.

Structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs

The paper determines the structure of PSI-LHCI from Cyanidium caldarium and investigates its evolutionary relationships with other red-lineage LHCs.

Importin-7-dependent nuclear localization of the Flavivirus core protein is required for infectious virus production.

This study identifies importin-7 as a nuclear carrier for Flaviviridae core proteins and shows its requirement for infectious virus production.

Establishing a comprehensive web-based analysis platform for Nicotiana benthamiana genome and transcriptome

The paper develops a web-based platform for analyzing Nicotiana benthamiana genome and transcriptome data, enabling gene expression visualization, phylogenetic analysis, and functional enrichment.

The odor of a nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, is detected by specific olfactory sensory neurons of the green spotted puffers.

The study identifies a specific group of olfactory sensory neurons in green spotted puffers that respond to the nontoxic TTX analog TDT, supporting its role as a chemosensory cue for conspecific attraction and prey detection.

Induction of plant disease resistance by mixed oligosaccharide elicitors prepared from plant cell wall and crustacean shells

This study compares the elicitor activities of different oligosaccharides from plant cell walls and crustacean shells, showing that a mixture enhances disease resistance in tomato without inhibiting growth.

Retrovirus-derived RTL9 plays an important role in innate antifungal immunity in the eutherian brain

The paper shows RTL9, a retrovirus-derived gene, is essential for microglial antifungal immunity by degrading fungal zymosan in the brain.

Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in severe COVID-19

This study shows that combining an oral antiviral with a corticosteroid improves treatment outcomes in delayed SARS-CoV-2 infection in hamsters compared to monotherapy.

An inducible germ cell ablation chicken model for high-grade germline chimeras

This paper develops a drug-inducible germ cell ablation system in chickens to improve the efficiency of generating germline chimeras through transplanted gene-edited primordial germ cells.

Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist

This study identifies KSI-6666 as a pseudoirreversible S1PR1 antagonist that suppresses inflammation through interaction with a methionine residue.

AtMYB50 regulates root cell elongation by upregulating PECTIN METHYLESTERASE INHIBITOR 8 in Arabidopsis thaliana

The paper identifies MYB50 as a transcription factor regulated by UPB1 that promotes root cell elongation by upregulating PMEI8 in Arabidopsis thaliana.

Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy

This study uses a Drosophila model to distinguish between loss-of-function and dominant negative OPA1 mutations in DOA and DOA plus.