Author

N. Sheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:metagenomics· 1 Organism:yeast· 1

Frequent Co-Authors

A. Esberg· 1 shared C. He· 1 shared C. Källestal· 1 shared C. Tang· 1 shared D. C. Wallace· 1 shared D. Yu· 1 shared E. Johansson· 1 shared E. Seifert· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperMicrobiology

A. Esberg

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2

L. Xu, D. Yu, M. Xu, L.-X. Yang, Q.-C. Zou, X.-L. Feng, M.-H. Li, N. Sheng, Y.-G. Yao

This study identifies BTN3A2 as a primate-specific gene that inhibits SARS-CoV-2 infection by reducing ACE2 expression and blocking viral attachment.

bioRxiv · Jan 13, 2024Cell Biology

Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology

S. Maharjan, H. Gamper, Y. Yamaki, R. Y. Henley, N. Sheng, T. Suzuki, T. Suzuki, J. A. Piccirilli, M. Wanunu, E. Seifert, D. C. Wallace, Y.-M. Hou

The paper shows that N1-methylation at position 9 of mt-Leu(UAA) stabilizes wild-type mt-tRNA but destabilizes pathogenic variants, suggesting methylation control could be therapeutic.

bioRxiv · Dec 9, 2023Cell Biology

Initial niche condition determines the aging speed and regenerative activity of quiescent cells

Q. Liu, N. Sheng, Z. Zhang, C. He, Y. Zhao, H. Sun, J. Chen, X. Yang, C. Tang

This study shows that initial niche conditions determine the aging speed and regenerative activity of quiescent fission yeast cells, with regenerative activity declining linearly before survivability.

bioRxiv · Sep 6, 2022 · PreprintCell Biology

Dynamics, cariogenicity, and geographic distribution of Streptococcus mutans adhesin types suggest adaptation to individual hosts

N. Sheng, A. Esberg, l. marell, E. Johansson, C. Källestal, N. Strömberg

The paper tracks the stability and geographic distribution of Streptococcus mutans adhesin types over 5 years and links specific subtypes to increased caries risk.

bioRxiv · Jan 7, 2019 · PreprintMicrobiology