Personalized multi-assay profiling of respiratory motile ciliopathies and mRNA therapy
Georgia N. Ithakisiou, Pim Cleijpool, Henriette H. M. Raeven, Bram M. Bosch, Wessel Hornman, Daniëlle Hoenselaar, Marinos Tziouvelis, Aranka Gerritsen, Matthew B. Smith, Loes A. Oosterhoff, R.B. Bhattacharjee, Zechen Wang, T. Noelle Lombana, Brandon A. Wustman, Cornelis Korstiaan van der Ent, , Bahar Yetkin-Arik
This study develops a personalized multi-assay platform using nasal epithelial cells to assess ciliary function and therapeutic response in primary ciliary dyskinesia.
bioRxiv · May 23, 2026 · PreprintCell Biology