Bram M. Bosch

UDIST separates shape and texture in microscopy images into independent latent subspaces, enabling unbiased phenotypic analysis across biological scales.

This study develops a personalized multi-assay platform using nasal epithelial cells to assess ciliary function and therapeutic response in primary ciliary dyskinesia.

The paper describes the immortalization of human nasal and bronchial airway epithelial cells using hTERT overexpression, enabling long-term genome editing studies.