Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis
Biren M. Dave, Xin Chen, Fraser P. McCready, Connor S. Charton, Rachel M. Morley, Jignesh K. Tailor, James Ellis, Xi Huang, Peter B. Dirks
This study differentiates human hindbrain neuroepithelial stem cells into cerebellar granule neurons in vitro, recapitulating key progenitor states and showing SHH's role in lineage specification and maturation.
Development · Jun 29, 2023Peer-reviewedDevelopmental Biology