Xi Huang

This study identifies metabolic partnerships between medulloblastoma and macrophages that drive leptomeningeal metastases and suggests targeting the CXCL12-SCARB1-cholesterol axis as a therapeutic strategy.

This study shows PIEZO channels are essential for intestinal stem cell maintenance by sensing mechanical cues from their niche.

The paper shows that fibronectin-dependent tissue stiffness controls durotaxis and cell rearrangements through a phase transition model in mouse limb bud mesoderm.

This study differentiates human hindbrain neuroepithelial stem cells into cerebellar granule neurons in vitro, recapitulating key progenitor states and showing SHH's role in lineage specification and maturation.

This study identifies a role for the Drosophila voltage-gated sodium channel, paralytic, in regulating neural progenitor proliferation and tumor suppression.