Author

Rachel McNeel

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:proteomics· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alan K. JarmuschiD· 2 shared Artjola PujaiD· 2 shared Francisco Manuel Nadal-NicolásiD· 2 shared Jianhai DuiD· 2 shared Kirsten E. OverdahliD· 2 shared Kiyoharu J. MiyagishimaiD· 2 shared Siyan Zhu· 2 shared David HansmaniD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Alan K. JarmuschORCID

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Author profile →

4 papers

Recent·Most cited

Aging Differentially Remodels the Retina and RPE/Choroid Proteome and Metabolism

Siyan Zhu, Artjola Puja, Rachel McNeel, Diana Alabdallat, Tuan Ngo, Jianhai Du

This study identifies age-related proteomic and metabolic changes in the retina and RPE/Cho of mice, revealing tissue-specific and age-dependent shifts in metabolic pathways.

bioRxiv · Oct 9, 2026 · PreprintBiochemistry

Exosomal Profiling Reveals Mechanisms of Hibernation-Associated Neuroprotection

Francisco Manuel Nadal-Nicolás, Rachel McNeel, Kirsten E. Overdahl, Alan K. Jarmusch, Kiyoharu J. Miyagishima

This study identifies metabolic and exosomal mechanisms of neuroprotection in hibernating thirteen-lined ground squirrels following optic nerve injury.

bioRxiv · Jun 29, 2026 · PreprintNeuroscience

Metabolic Intervention with Dimethyl Malonate Impairs Phagocytic Clearance but Fails to Protect Neurons

Rachel McNeel, Francisco Manuel Nadal-Nicolás, Kirsten E. Overdahl, Wei Li, Alan K. Jarmusch, Kiyoharu J. Miyagishima

This study tests if inhibiting succinate oxidation with dimethyl malonate protects neurons after optic nerve injury but finds it impairs phagocytosis and fails to reduce inflammation.

bioRxiv · Jun 2, 2026 · PreprintCell Biology

Early proteomic signatures of Alzheimer`s disease in the retina and brain of 3xTg-AD mice

Artjola Puja, Rachel McNeel, Rong Xu, Siyan Zhu, David Hansman, Jianhai Du

This study identifies early proteomic changes in the retina and brain of 3xTg-AD mice, revealing shared and tissue-specific metabolic and transport dysregulation linked to Alzheimer's disease.

Frontiers in Cell and Developmental Biology · May 18, 2026Peer-reviewedBiochemistry