Francisco Manuel Nadal-Nicolás

This study identifies metabolic and exosomal mechanisms of neuroprotection in hibernating thirteen-lined ground squirrels following optic nerve injury.

This study tests if inhibiting succinate oxidation with dimethyl malonate protects neurons after optic nerve injury but finds it impairs phagocytosis and fails to reduce inflammation.

The paper identifies ATF2 phosphorylation as a key driver of neuron apoptosis and shows that inhibiting ATF2 protects neurons in culture and in vivo.

This study develops a human iPSC model of axonal degeneration, identifies DLK-dependent mitochondrial fission as a key mechanism, and shows CRISPR-mediated Drp1 depletion protects neurons from degeneration.

The paper identifies Nrxn3 as essential for S-cone to SCBC synapse specificity in the mammalian retina using ground squirrel transcriptomes and transgenic mouse models.

The paper identifies a new inhibitory retinal amacrine cell type, MAC, that forms direct electrical and chemical synapses with Müller glia, revealing neuron-glia coupling in the mammalian retina.