Author

RAJ KUMAR PANDITA

Houston Methodist Research Institute

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Neuroscience· 1

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Organism:Drosophila· 1 Approach:experimental assay· 1

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Annie Tao· 1 shared Charlene Smith-GeateriD· 1 shared Chi-Lin TsaiiD· 1 shared Cornelis J. ElferinkiD· 1 shared Devon F. Pandlebury· 1 shared Francis Leonard· 1 shared John A. TaineriD· 1 shared Keegan M. BushiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperNeuroscience

Annie Tao

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintSep 19, 2024

Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons

Subrata Pradhan, Keegan M. Bush, Nan Zhang…·Partha S. Sarkar

This study identifies a mechanism where HTT recruits BRG1 and NHEJ components to repair transcription-associated DSBs in neurons, and shows that mutant HTT impairs this process, contributing to HD pathology.

3 citations

Drosophilaexperimental assay

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