Investigation of TRMT61B methyltransferase activity on mRNA and its effects on translation
Dorthy Fang, John M. Babich, Ryan Stanton, Isaac W. Vock, Kyrillos Abdallah, Mingyi Zhu, Raj Letchuman, Richard Li, Matthew D. Simon, Wendy V. Gilbert, Sigrid Nachtergaele
This study identifies TRMT61B as an m1A methyltransferase active on cytosolic mRNAs and shows context-dependent effects of m1A on translation and ribosome recruitment.
Nucleic Acids Research · Apr 10, 2026Peer-reviewedBiochemistry