Mingyi Zhu

This study identifies TRMT61B as an m1A methyltransferase active on cytosolic mRNAs and shows context-dependent effects of m1A on translation and ribosome recruitment.

The paper shows that 40S ribosomal subunits scan mRNA via one-dimensional diffusion rather than helicase-driven translocation in yeast.

The paper investigates the structural determinants of inverted Alu-mediated backsplicing in the HIPK3 gene using SHAPE-JuMP and finds that long-range Alu-mediated base pairs are required for circularization, but not full-length Alu elements.

DecoyFinder identifies contaminant sequences in homologous RNA sets using machine learning trained on TurboFold features, detecting 45% of non-homologs with 5% false positives.

The paper identifies dsRNA structures in uORFs that regulate translation and shows ASO targeting can modulate mORF translation and reduce cardiac hypertrophy.