Author

Rajamannar Thennati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alejandra TomásiD· 1 shared Ben J. JonesiD· 1 shared Gaëlle CarratiD· 1 shared Guy A. RutteriD· 1 shared Isabelle LeclerciD· 1 shared Muthukumaran NatarajaniD· 1 shared Piero MarchettiiD· 1 shared Pradeep Kumar Shahi· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alejandra TomásORCID

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1 paper

Recent·Most cited

Binding Kinetics, Bias, Receptor Internalization and Effects on Insulin Secretion in vitro and in vivo of a Novel GLP-1R/GIPR Dual Agonist, HISHS-2001

Yusman Manchanda, Ben J. Jones, Gaëlle Carrat, Zenouska Ramchunder, Piero Marchetti, Isabelle Leclerc, Rajamannar Thennati, VINOD S. BURADE, Muthukumaran Natarajan, Pradeep Kumar Shahi, Alejandra Tomás, Guy A. Rutter

This paper describes the synthesis and properties of a novel dual GLP-1R/GIPR agonist, HISHS-2001, showing improved pharmacological profile compared to tirzepatide in vitro and in vivo.

Diabetes Obesity and Metabolism · Aug 20, 2025Peer-reviewedPharmacology & Toxicology