Immunosuppressants Rewire the Gut Microbiome-Alloimmune Axis Through Time-Dependent and Tissue-Specific Mechanisms
Long Wu, Allison Kensiski, Samuel J. Gavzy, Yang Song, Hnin Wai Lwin, Michael France, Dejun Kong, Lushen Li, Ram Lakhan, Vikas Saxena, Wenji Piao, Marina Willson Shirkey, Valeria R. Mas, Brendan James Lohmar, Yan Shu, , Bing Ma
This study examines how four immunosuppressants alter the gut microbiome and immune responses over time, revealing drug-specific and tissue-dependent effects on microbial composition and lymphoid architecture.
Cell Communication and Signaling · Nov 26, 2025Peer-reviewedImmunology