Allison Kensiski

Immunosuppressants Rewire the Gut Microbiome-Alloimmune Axis Through Time-Dependent and Tissue-Specific Mechanisms

This study examines how four immunosuppressants alter the gut microbiome and immune responses over time, revealing drug-specific and tissue-dependent effects on microbial composition and lymphoid architecture.

Rapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome

This study investigates how rapamycin modulates lymph node architecture, leukocyte trafficking, and gut microbiome over time, revealing a novel mechanism of immunosuppression.

Regulatory T cells crosstalk with tumor and endothelium through lymphotoxin signaling

This study identifies Treg-mediated lymphotoxin signaling that promotes tumor growth and metastasis by activating nonclassical NFκB pathways in tumor and endothelial cells, and shows that targeting this pathway can suppress tumor progression.