Tubulin hyperacetylation drives HMGB1 nuclear exit via the ROS-PARP1 axis leading to rotenone-induced G2/M Arrest
Sourav Dutta, Semanti Chakraborty, Ayushi Ghosh, Priyadarshini Halder, Shubhra Majumder, Ratnadip Paul, Somsubhra Nath, Piyali Mukherjee
The paper identifies a pathway where tubulin hyperacetylation and ROS-PARP1 signaling drive HMGB1 nuclear exit, leading to G2/M arrest induced by rotenone.
Journal of Biological Chemistry · Sep 8, 2025Peer-reviewedCell Biology