Invariant Differential Expression Analysis Reveals Mechanism of Cancer Resistance to Cell Cycle Inhibitors
Amit Chatterjee, Sonalisa Pandey, Ravikanth Danda, R. Ranjith Kumar, S. Uma Maheswari, Vikas Khetan, Pukhraj Rishi, Sundara Ramaprabhu, Sailaja V Elchuri, Debashis Sahoo
The paper introduces iDEA, a method to improve differential expression analysis in cancer, revealing mechanisms of resistance to cell cycle inhibitors in retinoblastoma.
bioRxiv · Feb 17, 2021 · PreprintSystems Biology