Developmental BiologyPLoS GeneticsPeer-reviewed
Low Affinity Binding Sites in an Activating CRM Mediate Negative Autoregulation of the Drosophila Hox Gene Ultrabithorax
Rebecca K. Delker, Vikram Ranade, Ryan Loker…·Richard S. Mann
The paper identifies a negative autoregulatory loop mediated by low-affinity Ubx-Exd binding sites in the Drosophila Hox gene Ultrabithorax, maintaining differential expression levels in distinct compartments.
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