Cell-free glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein
Johannes Ruhnau, Valerian Grote, Mariana Juarez-Osorio, Dunja Bruder, Reza Mahour, Erdmann Rapp, Thomas Rexer, Udo Reichl
The paper describes an in-vitro glycoengineering approach to modify N-glycans on recombinant SARS-CoV-2 spike glycoprotein to mimic mammalian cell-derived glycoforms.
Frontiers in Bioengineering and Biotechnology · Aug 16, 2021Peer-reviewedSynthetic Biology