Erdmann Rapp

This study identifies sulfated and O-acetylated N-glycans at specific sites in human IgA using a targeted N-glycoproteomic approach, revealing their potential as biomarkers and therapeutic targets.

This study compares glycosylation, infectivity, and neutralization sensitivity of SIV produced in macrophages versus CD4+ T cells, revealing differences in glycan profiles and their impact on viral spread and antibody neutralization.

The paper develops an improved N-glycoproteomic workflow to analyze low-abundant glycoproteins in human blood plasma, enabling the identification of 1,929 N-glycopeptides and 942 N-glycosites.

The paper describes an in-vitro glycoengineering approach to modify N-glycans on recombinant SARS-CoV-2 spike glycoprotein to mimic mammalian cell-derived glycoforms.

The paper models a hypo-N-glycosylation disorder in medaka fish, showing reduced N-glycan abundance and retinal degeneration, with mRNA rescue restoring viability.