Author

Rian DelVecchio

University of North Carolina at Chapel HillPrimary ORCID profile (0009-0003-3902-1650 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Rian DelVecchioiD1 paper · Indiana University School of Medicine

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Adeleye James AfolayaniD· 1 shared Chathura PaththamperumaiD· 1 shared Colleen M. McCanniD· 1 shared Erica Fennimore· 1 shared Ethan PaulаkonisiD· 1 shared Huaqun Zhang· 1 shared Ivy Peng· 1 shared Jay C. Nix· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adeleye James AfolayanORCID

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1 paper

Recent·Most cited

Phosphorylation-State Modulated Binding of HSP70: Structural Insights and Compensatory Protein Engineering

Mariah S. Stewart, Chathura Paththamperuma, Colleen M. McCann, Kelsey Cottingim, Huaqun Zhang, Rian DelVecchio, Ivy Peng, Erica Fennimore, Jay C. Nix, Morcos N Saeed, Kathleen George, Katherine Makaroff, Meagan Colie, Ethan Paulаkonis, Michael Fernandes de Almeida, , Jonathan Cummings Schisler

This study examines how phosphorylation at HSP70 T636 affects its binding to CHIP, showing reduced affinity and altered interactions with other co-chaperones, with implications for disease.

bioRxiv · Feb 17, 2025 · PreprintBiochemistry