Author

Ricardo A. M. Serafim

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Pharmacology & Toxicology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

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Alessandra Mascarello· 1 shared Alison D. Axtman· 1 shared Carrow I. Wells· 1 shared Cristiano R. W. Guimarães· 1 shared David H. Drewry· 1 shared Hátylas Azevedo· 1 shared Jonathan M. Elkins· 1 shared Opher Gileadi· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperPharmacology & Toxicology

Alessandra Mascarello

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMar 2, 2017

Development of Narrow Spectrum ATP-competitive Kinase Inhibitors as Probes for BIKE and AAK1

Rafael M. Couñago, Alison D. Axtman, Stephen J. Capuzzi…·William J. Zuercher

The paper describes two compounds with minimal structural differences that show significant differential kinase activity, using x-ray crystallography and computational analysis to explain the selectivity.

DOI 10.1101/094631

experimental assaydrug response / drug discovery

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