NeuroscienceJournal of PainPeer-reviewed
Convergent state-control of endogenous opioid analgesia
Blake A. Kimmey, Lindsay L. Ejoh, Lily Shangloo…·Gregory F. Corder
The paper identifies a functional dichotomy in the ventrolateral periaqueductal gray, showing that micro opioid receptor neurons encode nociceptive states while enkephalin-releasing neurons drive pain relief in various contexts.