Author

Richard G. Hibbert

The Netherlands Cancer Institute

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Molecular Biology· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Akiyo HayashiiD· 1 shared Anastassis Perrakis AiD· 1 shared Christophe CaillatiD· 1 shared Eleonore von CastelmuriD· 1 shared Hideo NishitaniiD· 1 shared Magda Stadnik-SpiewakiD· 1 shared Michiyo Takahara· 1 shared Naohiro Suenaga· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Akiyo HayashiORCID

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1 paper

Recent·Most cited

Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1

Akiyo Hayashi, Nikolaos-Nikiforos Giakoumakis, Tatjana Heidebrecht, Takashi Ishii, Ανδρέας Παναγόπουλος, Christophe Caillat, Michiyo Takahara, Richard G. Hibbert, Naohiro Suenaga, Magda Stadnik-Spiewak, Tatsuro S. Takahashi, Yasushi Shiomi, Stavros L. Taraviras, Eleonore von Castelmur, Zoi Lygerou, , Hideo Nishitani

The paper shows that Cdt2 binds PCNA via a PIP box, enhancing CRL4Cdt2 activity and Cdt1 ubiquitination, suggesting a new mechanism for substrate targeting.

Life Science Alliance · Dec 1, 2018Peer-reviewedMolecular Biology