The Drosophila PDGF/VEGF signaling pathway regulates host immunometabolism in response to parasitoid infection
Ashley L. Waring, Abraham Y. Kpirikai, Jun Yang, Riitvek Baddireddi, Najeeb Marun, Nicholas M. Bretz, Helen Gosnell, Humayl Malik, David A. Hendrix, Nathan T. Mortimer
This study identifies the PDGF/VEGF signaling pathway as a key driver of immunometabolism in Drosophila during parasitoid wasp infection, revealing a trade-off between immune function and development.
bioRxiv · Oct 1, 2025 · PreprintBiochemistry