Author

Nicholas M. Bretz

Oregon State UniversityORCID 0000-0003-4481-7381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Nathan T. MortimeriD· 3 shared Ashley L. WaringiD· 2 shared Abraham Y. KpirikaiiD· 1 shared Brooke M. AlleniD· 1 shared Chris Lark· 1 shared Dakota FussiD· 1 shared David A. HendrixiD· 1 shared Helen Gosnell· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

Nathan T. MortimerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 1, 2025

The Drosophila PDGF/VEGF signaling pathway regulates host immunometabolism in response to parasitoid infection

Ashley L. Waring, Abraham Y. Kpirikai, Jun Yang…·Nathan T. Mortimer

This study identifies the PDGF/VEGF signaling pathway as a key driver of immunometabolism in Drosophila during parasitoid wasp infection, revealing a trade-off between immune function and development.

DOI 10.1101/2025.10.01.679819

Drosophilaexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 8, 2025

Venom vesicles from the parasitoid Ganaspis hookeri facilitate venom protein entry into host immune cells

Nicholas M. Bretz, Chris Lark, Sarah Perkel…·Nathan T. Mortimer

The paper investigates how venom vesicles from Ganaspis hookeri parasitoid wasps facilitate the entry of venom proteins, including SERCA, into host immune cells to suppress immune responses.

1 citation

Drosophilabiophysical modeling

𝕏 PostBluesky

GeneticsInsectsPeer-reviewedMay 23, 2022

Meta-analysis of immune induced gene expression changes in diverse Drosophila melanogaster innate immune responses

Ashley L. Waring, Joshua Hill, Brooke M. Allen…·Nathan T. Mortimer

The paper identifies conserved gene expression changes and transcription factor binding sites in Drosophila melanogaster across diverse immune responses to pathogens.

6 citations

Drosophilabulk RNA-seq

𝕏 PostBluesky