The Splicing Factor PTBP1 interacts with RUNX1 and is Required for Leukemia Cell Survival
Arjun Dhir, Alexander Ethell, Riley Watkins, Calvin K. Lam, Kevin Tur-Rodriguez, Jimmie Persinger, Kasidy K. Dobish, Sipra Panda, Shannon M. Buckley, Samantha A. Swenson, Sandipan Brahma, M. Jordan Rowley, R. Katherine Hyde
The paper identifies PTBP1 as a RUNX1 interacting partner required for leukemia cell survival through metabolic gene regulation.
Leukemia · Nov 10, 2025Peer-reviewedCancer Biology