Author

Alexander Ethell

Fred and Pamela Buffett Cancer CenterORCID 0000-0002-6047-4115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

M. Jordan RowleyiD· 2 shared Allyson Schmitz· 1 shared Angus Y. Lee· 1 shared Arjun DhiriD· 1 shared Ben NolaniD· 1 shared Bryan ChimiD· 1 shared Calvin K. LamiD· 1 shared Chen‐Yu ZhangiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

M. Jordan RowleyORCID

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Author profile →

3 papers

Recent·Most cited

Guanine content in the CTCF motif encodes a vulnerability to persistent, alcohol-induced redistribution

Ben Nolan, Joynob Akter Puspo, Iesha M Querry-Peterson, Stephanie Maurina, Rebecca A Wright, Allyson Schmitz, Lauren E Jacobsen, Coralmarie Ortiz, Timothy E. Reznicek, Alexander Ethell, Hannah L. Harris, Christopher T. Cummings, M. Jordan Rowley

The paper shows alcohol exposure disrupts chromatin by altering CTCF and cohesin occupancy at guanine-rich sites, leading to lasting gene expression changes.

bioRxiv · Oct 16, 2026 · PreprintMolecular Biology

The Splicing Factor PTBP1 interacts with RUNX1 and is Required for Leukemia Cell Survival

Arjun Dhir, Alexander Ethell, Riley Watkins, Calvin K. Lam, Kevin Tur-Rodriguez, Jimmie Persinger, Kasidy K. Dobish, Sipra Panda, Shannon M. Buckley, Samantha A. Swenson, Sandipan Brahma, M. Jordan Rowley, R. Katherine Hyde

The paper identifies PTBP1 as a RUNX1 interacting partner required for leukemia cell survival through metabolic gene regulation.

Leukemia · Nov 10, 2025Peer-reviewedCancer Biology

Binary outcomes of enhancer activity underlie stable random monoallelic expression

Djem U. Kissiov, Alexander Ethell, Sean Chen, Natalie K. Wolf, Chen‐Yu Zhang, Susanna M. Dang, Yeara Jo, Katrine N. Madsen, Ishan Paranjpe, Angus Y. Lee, Bryan Chim, Stefan Adi Muljo, David H. Raulet

The paper investigates enhancer activity's role in random monoallelic expression (RME) of NK cell receptor genes, finding that enhancer properties drive RME and suggest it is a general phenomenon.

eLife · Mar 22, 2022Peer-reviewedMolecular Biology