Unique recognition, phagocytosis, and intracellular survival of Cryptococcus neoformans in a human immortalized microglia cell line
Robbi L. Ross, Kassandra Arias-Parbul, Zane M. Douglass, Katrina L. Adams, Felipe Hiram Santiago-Tirado
This study investigates how human microglia interact with Cryptococcus neoformans, showing limited phagocytic activity and ineffective killing of the fungus due to its ability to disrupt phagosome maturation.
bioRxiv · Jul 17, 2025 · PreprintMicrobiology