Author

Kassandra Arias-Parbul

University of Notre DameORCID 0000-0002-3083-7528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Felipe Hiram Santiago-TiradoiD· 2 shared Alyssa Ann La BellaiD· 1 shared Ana Lidia Flores‐MirelesiD· 1 shared Armando M. MarrufoiD· 1 shared Christopher GageriD· 1 shared Deborah L. DonahueiD· 1 shared Elizabeth R. LucasiD· 1 shared Ellsa Wongso· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Felipe Hiram Santiago-TiradoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Unique recognition, phagocytosis, and intracellular survival of Cryptococcus neoformans in a human immortalized microglia cell line

Robbi L. Ross, Kassandra Arias-Parbul, Zane M. Douglass, Katrina L. Adams, Felipe Hiram Santiago-Tirado

This study investigates how human microglia interact with Cryptococcus neoformans, showing limited phagocytic activity and ineffective killing of the fungus due to its ability to disrupt phagosome maturation.

bioRxiv · Jul 17, 2025 · PreprintMicrobiology

The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI

Armando M. Marrufo, Jonathan J. Molina, Christopher Gager, Marissa Jeme Andersen, Alyssa Ann La Bella, Elizabeth R. Lucas, Ellsa Wongso, Tamanna Urmi, Kassandra Arias-Parbul, Railyn Webster, Peter V. Stuckey, Kurt N. Kohler, Deborah L. Donahue, Victoria A. Ploplis, Matthew J. Flick, , Ana Lidia Flores‐Mireles

This study shows that fibrin accumulation in a catheterized bladder promotes anti-inflammatory macrophage polarization, which impairs antimicrobial responses and allows bacterial persistence in UTIs.

bioRxiv · Jul 16, 2024 · PreprintImmunology