BiochemistrybioRxivPreprint
Mitochondrial Signaling: Nitric Oxide Synthesis by Cytochrome c Oxidase and Its Oxygen Sensitivity Are Modulated by Adenine Nucleotides
Pablo Raúl Castello, Kerri A. Ball, Robert Ο. Poyton
The paper examines how adenine nucleotides modulate nitric oxide synthesis by cytochrome c oxidase in mitochondria, showing differential effects of ADP and ATP and isoform-specific responses under hypoxia.