U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs
Aykut Shen, Katarzyna Hencel, Matthew T Parker, Robyn Scott, Roberta Skukan, Aduragbemi S. Adesina, Carey L. Metheringham, Eric Alexander Miska, Yunsun Nam, Wilfried Haerty, Gordon Grant Simpson, Alper Akay
The paper shows that m6A modification of U6 snRNA by METT-10 is essential for accurate and efficient cis- and trans-splicing in C. elegans pre-mRNAs.
Nucleic Acids Research · May 29, 2024Peer-reviewedMolecular Biology