Author

Aykut Shen

University of East Anglia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alper AkayiD· 2 shared Katarzyna Hencel· 2 shared Aduragbemi S. AdesinaiD· 1 shared Alexei A. MaklakoviD· 1 shared Carey L. MetheringhamiD· 1 shared Daniel Clifton· 1 shared Eric Alexander MiskaiD· 1 shared Gordon Grant SimpsoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Alper AkayORCID

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2 papers

Recent·Most cited

U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs

Aykut Shen, Katarzyna Hencel, Matthew T Parker, Robyn Scott, Roberta Skukan, Aduragbemi S. Adesina, Carey L. Metheringham, Eric Alexander Miska, Yunsun Nam, Wilfried Haerty, Gordon Grant Simpson, Alper Akay

The paper shows that m6A modification of U6 snRNA by METT-10 is essential for accurate and efficient cis- and trans-splicing in C. elegans pre-mRNAs.

Nucleic Acids Research · May 29, 2024Peer-reviewedMolecular Biology

Optimising age-specific insulin signalling to slow down reproductive ageing increases fitness in different environments

Zahida Sultanova, Aykut Shen, Katarzyna Hencel, Hanne Carlsson, Zoe Crighton, Daniel Clifton, Alper Akay, Alexei A. Maklakov

The paper shows that optimizing insulin signaling in adulthood improves late-life reproduction and fitness in C. elegans across different environments.

bioRxiv · Dec 22, 2023 · PreprintEvolutionary Biology