Alper Akay

This paper develops a high-throughput method using E. coli to detect and quantify vitamin B12 from microbiome isolates, revealing differences in vitamin B12 production.

The paper shows that m6A modification of U6 snRNA by METT-10 is essential for accurate and efficient cis- and trans-splicing in C. elegans pre-mRNAs.

The paper shows that optimizing insulin signaling in adulthood improves late-life reproduction and fitness in C. elegans across different environments.

This paper develops methods for delivering macromolecules and expressing exogenous mRNA in plant-parasitic nematodes, advancing functional genetic tools for these pests.

This study shows that m5C RNA modification in C. elegans affects translation efficiency and adaptation to heat stress by modulating leucine and proline decoding.

This study identifies RPB-9 as essential for piRNA-mediated silencing in C. elegans by promoting transcriptional elongation/termination at piRNA loci.

The paper identifies and functionally characterizes long non-coding RNAs in C. elegans using transcriptome analysis and CRISPR/Cas9 mutagenesis.

This study identifies the Aquarius/EMB-4 helicase as essential for initiating small RNA-induced co-transcriptional gene silencing in C. elegans by facilitating HRDE-1 complex engagement with nascent transcripts.

The paper shows that E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans when fed bacteria.