The Nuclear-Cytoskeletal Interface Is a Vulnerability in Aging Endothelium
Caitlin Francis, Felipe Saceanu Leser, Roberto Lopez, Anne Eichmann
This study identifies the nuclear-cytoskeletal interface as a vulnerability in aging endothelium, showing that Progerin disrupts this interface and impairs angiogenesis and lumen formation.
bioRxiv · Mar 12, 2026 · PreprintCell Biology