Caitlin R. Francis

This study identifies the nuclear-cytoskeletal interface as a vulnerability in aging endothelium, showing that Progerin disrupts this interface and impairs angiogenesis and lumen formation.

This study investigates the role of endothelial Rho kinase (ROCK1/2) in vascular integrity and angiogenesis, finding that their loss leads to vascular defects and lethality.

This study investigates Arf6's role in angiogenesis by analyzing its impact on actin assembly and clathrin-mediated endocytosis in endothelial cells.

This study identifies Rab35's role in regulating actin dynamics to establish apicobasal polarity during sprouting angiogenesis.

This study shows that Slp2a is essential for vascular lumen formation by regulating Weibel-Palade body exocytosis and angiopoietin-2 release during angiogenesis.