A basophil-specific GPCR mediates the immune response to helminth infection
Aleksander Geske, Rong Pan, Celeste Flores, Taylor Follansbee, Nathachit Limjunyawong, Dona Ridma Harindri Sirimanna, Xintong Dong, Xinzhong Dong
This study identifies Mrgpra6 as a basophil-specific GPCR essential for host defense against helminth infection, showing its role in innate immunity and parasite control.
bioRxiv · Aug 21, 2026 · PreprintImmunology