Cell BiologybioRxiv
Nanog fluctuations in ES cells highlight the problem of measurement in cell biology
Rosanna C G Smith, Patrick S Stumpf, Sonya J Ridden…·Ben D MacArthur
The paper shows that genetic reporters for Nanog can distort its dynamics in ES cells, leading to misleading results about pluripotency regulation.
DOI 10.1016/j.bpj.2017.05.005