GeneticsbioRxivPreprint
A Drosophila Wolfram Syndrome 1 (WFS1) homologue synergises with the intracellular Ca2+ release channel, IP3R to affect mitochondrial morphology and function
Rose Sebastian Kunnappallil, Gaiti Hasan
This study shows that WFS1 interacts with IP3R in Drosophila dopaminergic neurons to regulate mitochondrial morphology and function, and that mutations in these genes cause flight deficits.