Author

Roshan R. Rajamanickam

La Jolla Institute for Immunology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:virus· 1

Frequent Co-Authors

Dawid S. ZylaiD· 2 shared Erica Ollmann SaphireiD· 2 shared Kathryn M. HastieiD· 2 shared Rubén Díaz-AvalosiD· 2 shared Stephanie HarkinsiD· 2 shared Cassandra Yu· 1 shared Chen SuniD· 1 shared Chitra HariharaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

Dawid S. ZylaORCID

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2 papers

Recent·Most cited

BiochemistryScience AdvancesPeer-reviewedAug 27, 2025

Human endogenous retrovirus K (HERV-K) envelope structures in pre- and post-fusion by Cryo-EM

Jeremy Shek, Chen Sun, Elise M. Wilson…·Erica Ollmann Saphire

This study determines the pre- and post-fusion structures of HERV-K Env using cryo-EM, revealing unique features that may inform therapeutic strategies.

4 citations

humancryo-EM

𝕏 PostBluesky

MicrobiologyCell ReportsPeer-reviewedJul 22, 2025

Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation

Eduardo Olmedillas, Roshan R. Rajamanickam, Rubén Díaz-Avalos…·Erica Ollmann Saphire

This study presents a pre-fusion, open conformation of the SARS-CoV-2 S2 subunit and identifies antibodies that recognize it, providing insights into spike dynamics and potential vaccine targets.

22 citationstop 1%

viruscryo-EM

𝕏 PostBluesky