Logic-Gated Fluorogenic RNA Reporters for Multiplexed Live-Cell Imaging
Sima Khajouei, Ali Ebrahimi Darsinouei, Ru Zheng, Jeffrey Chen, Qinge Liu, Zhaolin Xue, Mingxu You
The paper introduces logicFRIES, a fluorogenic RNA platform enabling eight-plex live-cell imaging through logic-gated activation and sequential fluorescence imaging.
bioRxiv · Aug 21, 2026 · PreprintMolecular Biology