Mingxu You

The paper introduces logicFRIES, a fluorogenic RNA platform enabling eight-plex live-cell imaging through logic-gated activation and sequential fluorescence imaging.

This paper develops programmable RNA scaffolds that form synthetic condensates in mammalian cells, showing that double-stranded RNA stems drive assembly and introducing an allosteric switch for reversible control.

This paper develops a portable electrochemical DNA sensor for detecting piconewton-scale cellular forces using CRISPR-Cas12a for enhanced sensitivity and tunable threshold forces.